Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 Apr 16;62(5):1665–1675. doi: 10.2337/db12-0242

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2013 by the American Diabetes Association.

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

PMC Copyright notice

FIG. 1. — Allogeneic (BALB/c) or syngeneic (C57BL/6) islets were transplanted into diabetic C57BL/6 recipient mice and harvested at day 14 after transplantation. P2XR mRNA levels were compared with untransplanted BALB/c islets (Baseline). A: Higher P2X1R expression was evident in syngeneic and allogeneic transplanted islets compared with baseline (n = 3, **P < 0.01), whereas higher expression of P2X7R was observed specifically in the allogeneic graft (n = 3; *P < 0.05). Immunohistochemical analysis showed positive staining for P2X7 in infiltrating mononuclear cells with absence of staining in islet and kidney parenchymal cells by hematoxylin and eosin (H&E) (B) and P2X7R (C).