Table 1.
Component Score | Events per 1,000 pyrs | HR (95% CI), Unadjusted | HR (95% CI), Age, Sex, Race | C-Statistic (95% CI), Unadjusted* |
Systolic blood pressure | ||||
0 | 36 | 1.00 | 1.00 | |
1 | 37 | 1.05 (0.89–1.23) | 1.00 (0.85–1.17) | 0.530 (0.507–0.553) |
2 | 43 | 1.22 (1.05–1.42) | 1.13 (0.97–1.32) | |
Forced vital capacity | ||||
0 | 26 | 1.00 | 1.00 | |
1 | 37 | 1.43 (1.21–1.69) | 1.28 (1.07–1.51) | 0.534 (0.511–0.557) |
2 | 55 | 2.19 (1.87–2.56) | 1.85 (1.56–2.19) | |
DSST score | ||||
0 | 25 | 1.00 | 1.00 | |
1 | 39 | 1.61 (1.36–1.90) | 1.45 (1.23–1.72) | 0.634 (0.612–0.655) |
2 | 56 | 2.42 (2.06–2.85) | 1.97 (1.64–2.37) | |
Serum cystatin-C | ||||
0 | 27 | 1.00 | 1.00 | |
1 | 35 | 1.32 (1.12–1.57) | 1.26 (1.06–1.49) | 0.620 (0.598–0.642) |
2 | 54 | 2.09 (1.78–2.50) | 1.90 (1.61–2.24) | |
Serum fasting glucose | ||||
0 | 36 | 1.00 | 1.00 | |
1 | 37 | 1.05 (0.90–1.23) | 0.99 (0.85–1.16) | 0.538 (0.515–0.561) |
2 | 55 | 1.59 (1.34–1.89) | 1.42 (1.19–1.68) |
Notes: CI = confidence interval; DSST = Digit Symbol Substitution Test; HR = hazard ratio; and pyrs = person-years.
Unadjusted c-statistic for each component, modeled as a continuous variable, predicting death.