Table 5.
Comparison between Human Observers and Digital Imaging Systems in the Total Expression of Phosphorylated mTOR
| Method | Tissue | κ | Concordance Force |
|---|---|---|---|
| ScanScope × observer 1 | Control | 1.000 | Excellent |
| ScanScope × observer 2 | 1.000 | Excellent | |
| ACIS III × observer 1 | Control | 0.744 | Moderate |
| ACIS III × observer 2 | 0.744 | Moderate | |
| ScanScope × observer 1 | Grade I | 0.805 | Great |
| ScanScope × observer 2 | 0.908 | Excellent | |
| ACIS III × observer 1 | Grade I | 0.524 | Moderate |
| ACIS III × observer 2 | 0.643 | Great | |
| ScanScope × observer 1 | Grade II | 0.829 | Excellent |
| ScanScope × observer 2 | 0.872 | Excellent | |
| ACIS III × observer 1 | Grade II | 0.683 | Great |
| ACIS III × observer 2 | 0.645 | Great | |
| ScanScope × observer 1 | Grade III | 0.708 | Great |
| ScanScope × observer 2 | 0.571 | Moderate | |
| ACIS III × observer 1 | Grade III | 0.553 | Moderate |
| ACIS III × observer 2 | 0.429 | Moderate | |
| ScanScope × observer 1 | Grade IV | 0.915 | Excellent |
| ScanScope × observer 2 | 0.931 | Excellent | |
| ACIS III × observer 1 | Grade IV | 0.777 | Great |
| ACIS III × observer 2 | 0.827 | Excellent |