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. Author manuscript; available in PMC: 2014 Apr 2.
Published in final edited form as: Biochemistry. 2013 Mar 18;52(13):2337–2347. doi: 10.1021/bi400175d

Figure 4. Absence of the 669WTAPELL675 motif in ANF-RGC causes cardiac hypertrophy.

Figure 4

The ratio of the heart weight (in mg) to whole body weight (in g) of 10 weeks old 669WTAPELL675(+/+) wild type, 669WTAPELL675(+/−) heterozygous and 669WTAPELL675(−/−) homozygous was determined. The mice were fed a normal-salt diet. Bars indicate means ± SD values for the representative genotype. n describes the number of mice analyzed for each genotype. * indicates P <0.05.