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. Author manuscript; available in PMC: 2014 Apr 2.
Published in final edited form as: Biochemistry. 2013 Mar 18;52(13):2337–2347. doi: 10.1021/bi400175d

Figure 5. Deletion of the sequence coding for the 669WTAPELL675 motif from the ANF-RGC gene does not affect expression of the mutated cyclase in the kidney (A) and adrenal gland (B).

Figure 5

Cryosections of the kidney and adrenal gland from the wild type [669WTAPELL675(+/+)], heterozygous [669WTAPELL675(+/−)], and homozygous [669WTAPELL675(−/−)] mice were immuno-stained with ANF-RGC antibodies. The DIC image showing the integrity of the sections are also shown (“DIC”). Intense staining was observed in the renal apical and basolateral aspects of the tubular elements and adrenocortical zona glomerulosa.