Percentage changes from baseline in (A) LDL-C, (B) non-HDL-C, (C) triglycerides, and (D) HDL-C across dose range for each statin in the VOYAGER database.
Note: Copyright © 2010. Elsevier. Data reproduced from Nicholls SJ, Brandrup-Wognsen G, Palmer M, Barter PJ. Meta-analysis of comparative efficacy of increasing dose of atorvastatin versus rosuvastatin versus simvastatin on lowering levels of atherogenic lipids (from VOYAGER). Am J Cardiol. 2010;105:69–76.5
Copyright © 2010. The American Society for Biochemistry and Molecular Biology. Data reproduced from Barter PJ, Brandrup-Wognsen G, Palmer MK, Nicholls SJ. Effect of statins on HDL-C: a complex process unrelated to changes in LDL-C: analysis of the VOYAGER database. J Lipid Res. 2010;51:1546–1553.29
Abbreviations: LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol.