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A–H, Correlations of neurofilament light chain levels with regional proton-magnetic resonance spectroscopy–derived metabolite ratios. r represents the Spearman correlation coefficient and corresponding P value. Solid lines represent best-fit regression line, and dashed lines represent 95% confidence intervals. Abbreviations: Glu/Cr, glutamate/creatine; NAA/Cr, N-acetylaspartate/creatine; NFL, neurofilament light chain.
