Table 4.
Association of baseline variables with interstitial fibrosis/tubular atrophy score progression in univariate analysis
| Characteristic | Nonprogressors (n=151) | Progressors (n=114) | P Valuea |
|---|---|---|---|
| Male sex | 54.3 (82) | 58.8 (67) | 0.47 |
| Age at transplantation (yr) | 45.4±12.5 | 47.7±13.3 | 0.16 |
| Living donor | 27.3 (41) | 18.4 (21) | 0.09 |
| Donor age (yr) | 48.6±16.1 | 54.4±14.0 | 0.002 |
| Preemptive transplantation | 20.5(31) | 11.4(13) | 0.048 |
| Cold ischemia time | 0.19 | ||
| <250 min | 26.7 (39) | 18.0 (20) | |
| 250–1200 min | 35.6 (52) | 35.1 (39) | |
| >1200 min | 37.7 (55) | 46.8 (52) | |
| Delayed graft function | 20.5 (31) | 32.5 (37) | 0.03 |
| Acute cellular rejection before 3 months | 9.30 (14) | 11.4 (13) | 0.57 |
| Acute humoral rejection before 3 months | 7.90 (12) | 4.40 (5) | 0.24 |
| 3-month body mass index (kg/m2) | 23.7±3.92 | 23.6±3.84 | 0.83 |
| 3-month mGFR (ml/min per 1.73 m2) | 61.7±13.5 | 56.3±14.8 | 0.002 |
| 3-month 25(OH)D (ng/ml) | 16.8±10.1 | 13.2±7.00 | 0.001 |
| 3-month 1,25(OH)D (pg/ml) | 41.45±20.8 | 33.82±16.7 | 0.002 |
| 3-month PTH (pg/ml) | 84.0 (59.0–118.5) | 102.5 (64.0–180.0) | 0.01 |
| 3-month FGF-23 (RU/ml) | 62.0 (44.0–100.0) | 64.5 (44.8–102.8) | 0.62 |
Values are reported as percentage (number of patients), mean ± SD, or median (interquartile range), as appropriate.
a
P value represents tests of significance from t test, Wilcoxon test, or Pearson or Spearman correlation tests as appropriate.