Table 1.
Characteristics of participants in the overall cohort with at least one completed physical performance task and those with completed TUAG assessments
| Factor | Missing (n) | Overall (n=385) | Fast TUAG (n=240) | Slow TUAG (n=122) |
|---|---|---|---|---|
| Demographic data | 0 | |||
| Age (yr) | 61±13 | 57.7±12 | 66.4±12 | |
| Female | 63 (16) | 33 (14) | 26 (21) | |
| HMC | 158 (41) | 87 (36) | 56 (46) | |
| Seattle VAMC | 169 (44) | 117 (49) | 45 (37) | |
| Baltimore VAMC | 58 (15) | 36 (15) | 21 (17) | |
| Race | 0 | |||
| White | 239 (62) | 149 (62) | 73 (60) | |
| Other | 146 (38) | 91 (38) | 49 (40) | |
| Education | 30 | |||
| Some high school or less | 25 (7) | 12 (5) | 11 (10) | |
| Completed high school | 238 (67) | 144 (65) | 78 (70) | |
| Completed college or more | 92 (26) | 65 (29) | 23 (21) | |
| Current smoking | 10 | 62 (17) | 35 (15) | 24 (20) |
| Current alcohol use | 64 | 111 (35) | 79 (40) | 28 (28) |
| Physical examination data | ||||
| Systolic BP (mmHg) | 0 | 132.9±20.7 | 131.6±19.8 | 134.2±21.4 |
| BMI (kg/m2) | 0 | 31±6.9 | 30.2±6.3 | 32.5±7.7 |
| Waist circumference (in.) | 0 | 42.2±6.7 | 40.9±6 | 44.4±7.3 |
| Laboratory values | ||||
| eGFRcysc (ml/min per 1.73 m2)a | 58 | 47.6±23.3 | 51.7±24.8 | 41.1±18.3 |
| eGFR CKD-EPI (ml/min per 1.73 m2) | 0 | 41.3±19.3 | 43.6±19.9 | 37.8±17.5 |
| Creatinine (mg/dl) | 0 | 2.2±1.3 | 2.1±1.2 | 2.2±1.3 |
| Albuminuria (mg/g Cr) | 6 | 87.6 [11–630] | 94.7 [9.7–632] | 62.7 [11.7–575] |
| Hemoglobin (g/dl) | 16 | 12.8±1.9 | 13.1±1.9 | 12.5±1.9 |
| Bicarbonate (mmol/L) | 0 | 24.6±3.5 | 24.8±3.3 | 24.2±3.9 |
| CRP (mg/dl) | 29 | 5.2±7.7 | 4.5±7.1 | 5.8±7.6 |
| Cholesterol (mg/dl) | 0 | 177±56.6 | 181.1±57.7 | 170.9±55.3 |
| LDL (mg/dl) | 17 | 104.6±41.8 | 107.7±43.3 | 99.5±38 |
| HDL (mg/dl) | 0 | 40.3±17.3 | 41.3±19.2 | 38±13.6 |
| Triglycerides (mg/dl) | 0 | 163.4±120 | 169±131.8 | 159.5±102.5 |
| Albumin (mg/dl) | 0 | 3.8±0.6 | 3.9±0.6 | 3.8±0.6 |
| Phosphate (mg/dl) | 1 | 3.8±0.8 | 3.8±0.8 | 3.9±0.9 |
| Physical performance | ||||
| 4-m walk (m/s) | 63 | 0.9±0.2 | 1±0.2 | 0.7±0.2 |
| TUAG (sec) | 23 | 11.2±4.5 | 8.8±2 | 15.9±4.5 |
| 6-min walk (m) | 76 | 400±100.3 | 436.8±81.9 | 308.5±78.9 |
| Grip strength (kg) | 4 | 36.15±10.6 | 38.7±10.2 | 32.4±9.7 |
| Exercise (times per week)a | 70 | |||
| Never | 83 (26) | 41 (21) | 31 (33) | |
| <1 | 34 (11) | 24 (12) | 7 (8) | |
| 1 | 46 (15) | 28 (14) | 16 (17) | |
| 2–3 | 71 (23) | 46 (23) | 23 (25) | |
| >3 | 81 (26) | 61 (31) | 16 (17) | |
| Prevalent disease | 0 | |||
| Diabetes | 213 (55) | 118 (49) | 75 (61) | |
| Any CAD | 99 (26) | 48 (20) | 41 (34) | |
| Cancer | 54 (16) | 32 (15) | 17 (17) | |
| Disability | ||||
| Use of assistive device | 14 | 69 (19) | 18 (8) | 35 (29) |
| ≥1 ADL task | 54 | 27 (8) | 13 (6) | 10 (10) |
| ≥1 IADL taska | 65 | 112 (35) | 52 (26) | 49 (50) |
| ≥1 mobility taska | 64 | 77 (24) | 26 (13) | 37 (38) |
Values for categorical variables given as n (%), whereas values for continuous variables given as mean ± SD or median [25th– 75th percentile]. ADL, activity of daily living; IADL, instrumental activity of daily living.
a
Measured only in the SKS cohort.