Table 3.
Mean (± SEM) sucrose consumption and sucrose preference in male and female rats on the test day. Rats had received daily injections of saline or methylphenidate (2 or 5 mg/kg) for 10 consecutive days starting on PD 11.
| Pretreatment | Sucrose Consumption |
Sucrose Preference |
||
|---|---|---|---|---|
| Male | Female | Male | Female | |
| Saline | 14.0 (± 2.6)a | 8.7 (±1.5) | 66.6 (±6.8) | 64.1 (±11.2) |
| 2 mg/kg MPH | 15.0 (±1.7)a | 7.4 (±1.5) | 70.7 (±7.2) | 46.6 (±6.9) |
| 5 mg/kg MPH | 13.7 (±1.8)a | 8.9 (±1.0) | 65.4 (±8.4) | 60.5 (±7.0) |
Sucrose consumption is presented as the amount of 0.125% sucrose solution consumed (g) and sucrose preference is calculated as (weight of sucrose consumed / (weight of water consumed + weight of sucrose consumed) × 100).
a
Significantly different from female rats.