FIGURE 11.
Bacterial genome regions comprising putative sialyltransferases with homology to SiaDW-135. With the sialyltransferase domain identified in SiaDW-135 as template, a BLAST search was carried out and returned a number of bacterial proteins with weak homology. Although no function has yet been attributed to these proteins, all are encoded by genes (designated homologue CT and marked in red) that in the genome occur in close company with two other genes encoding enzymes of the sialylation pathway: the Neu5Ac9P-synthase (gene marked in green) and the CMP-Neu5Ac synthetase (gene marked in yellow). Bacteria harboring these homologues are named and the respective gene regions are schematically shown.