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. 2013 Feb 28;288(17):12222–12231. doi: 10.1074/jbc.M112.434225

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© 2013 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 8. — E-cadherin knockdown increases cell migration and invasion of prostate cancer cells. Representative time-lapsed images of wounded cultures in pBABE SPDEF PC3 (A, left panel, and B, upper panel) and LNCaP cells (C, left panel, and D, upper panel). Total magnification. 4×. The percentages of wound uncovered are plotted (B and D, upper panels). The yellow dotted lines represent the scratch gap at the time of wounding. Transwell Matrigel invasion assays of pBABE SPDEF PC3 (A, right panel, and B, lower panel) and LNCaP cells (C, right panel, and D, lower panel) are shown. **, p < 0.005.