FIGURE 3.

Antimicrobial and hemolytic activity of recombinant DEFB114. a, antimicrobial activity of the DEFB114 peptide against E. coli K12D31, S. aureus (CMCC 26003), and C. albicans (SC 5314) (2.0–4.0 × 10⁵ cfu/ml) was measured using cfu assays. b, salt-sensitive antimicrobial activity of DEFB114 (40 μg/ml) was determined in the absence or presence of 150 mm NaCl. c, concentration-dependent hemolytic effects of the recombinant DEFB114 peptide and LL-37 peptide. Treatment with 0.1% Triton X-100 served as a reference for complete hemolysis. The values represent the averages of three independent measurements with duplicate samples. Error bars, S.E.