Table 4.
Correlations between demographic and illness characteristics and neurocognitive performance for the total sample of 51 inpatients with therapy-resistant BD depression
|
Neurocognitive domain |
Demographic characteristics |
Course of illness |
Current symptoms |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| |
Gender (male) |
Age |
Education |
Premorbid IQ |
BD I |
Duration of illness |
Number of hospitalizations due to depresssive episodes |
History of psychotic symptoms |
Number of psychotic episodes |
Comorbid substance abuse |
Comorbid anxiety |
MADRS |
PANSS pos |
GAF-S |
| Test | (NART) | |||||||||||||
| Speed of Processing |
-0.09 |
-0.21 |
0.25 |
0.20 |
-0.25 |
-0.12 |
-0.02 |
-0.14 |
-0.10 |
0.09 |
0.02 |
0.05 |
-0.01 |
-0.05 |
| BACS–Symbol Coding |
-0.19 |
-0.29* |
0.28 |
0.27 |
-0.06 |
-0.27 |
-0.14 |
-0.04 |
0.01 |
0.08 |
0.17 |
-0.06 |
-0.15 |
0.06 |
| Fluency |
-0.09 |
-0.11 |
0.20 |
0.06 |
-0.35* |
0.10 |
0.22 |
-0.20 |
-0.24 |
0.01 |
0.05 |
-0.01 |
-0.05 |
0.17 |
| TMT-A |
-0.02 |
-0.19 |
0.23 |
0.14 |
-0.22 |
-0.15 |
-0.11 |
-0.09 |
-0.11 |
-0.01 |
-0.09 |
0.11 |
0.09 |
-0.22 |
| Attention/Vigilance |
-0.20 |
-0.46** |
0.14 |
0.00 |
-0.11 |
-0.43** |
-0.29 |
-0.08 |
-0.10 |
0.23 |
0.20 |
-0.19 |
-0.06 |
-0.10 |
| CPT |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Working memory |
-0.17 |
-0.43** |
0.36** |
0.16 |
-0.13 |
-0.27 |
-0.01 |
-0.07 |
-0.07 |
0.04 |
0.19 |
0.01 |
-0.20 |
0.05 |
| Spatial Span |
-0.10 |
-0.42** |
0.27 |
0.13 |
-0.12 |
-0.21 |
0.09 |
0.07 |
0.08 |
0.12 |
0.32 |
0.10 |
-0.20 |
0.00 |
| Letter-Number Span |
-0.17 |
-0.38** |
0.37** |
0.16 |
-0.11 |
-0.31* |
-0.10 |
-0.20 |
-0.20 |
-0.05 |
0.05 |
-0.05 |
-0.15 |
0.06 |
| Verbal learning |
-0.04 |
-0.37** |
0.32* |
0.36* |
-0.14 |
-0.25 |
-0.05 |
-0.20 |
-0.14 |
0.05 |
0.01 |
0.00 |
-0.25 |
0.02 |
| HVLT-R |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Visual learning |
-0.09 |
-0.28 |
0.34 |
0.16 |
-0.21 |
-0.14 |
0.17 |
-0.17 |
-0.12 |
0.12 |
0.23 |
-0.04 |
-0.14 |
0.03 |
| BVMT-R |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Reasoning |
-0.21 |
-0.19 |
0.22 |
0.04 |
0.04 |
-0.06 |
-0.13 |
0.10 |
0.08 |
0.18 |
0.21 |
0.07 |
0.02 |
-0.04 |
| Mazes |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Mean Composite score |
-0.18 |
-0.40** |
0.36** |
0.22 |
-0.19 |
-0.26 |
-0.07 |
-0.13 |
-0.12 |
0.10 |
0.15 |
-0.02 |
-0.13 |
-0.04 |
| IQ-decline |
-0.21 |
0.17 |
-0.41** |
-0.17 |
0.43** |
-0.05 |
0.17 |
0.40** |
0.41* |
-0.17 |
-0.01 |
0.05 |
0.26 |
-0.17 |
| NART-WASI | ||||||||||||||
Spearman’s rho is reported. *p < 0.05; **p < 0.01.