Table 1.
Morphometrical characteristics of intracellular fluorescent signal of type I and IV collagen fibroblasts from celiacs and healthy controls
| |
Type I collagen |
Type IV collagen |
||||
|---|---|---|---|---|---|---|
| Parameter | Controls (#12) | Celiacs (#12) | P value | Controls (#12) | Celiacs (#12) | P value |
| Feret Diameter (μm) * |
53.00 ± 11.00 |
35.20 ± 5.00 |
< 0.005 |
62.90 ± 12.05 |
32.90 ± 4.90 |
< 0.0001 |
| Perimeter (μm) |
121.30 ± 24.00 |
107.60 ± 16.80 |
< 0.005 |
145.90 ± 27.20 |
99.60 ± 12.06 |
< 0.001 |
| Area (μm2) |
377.20 ± 86.90 |
563.40 ± 122.80 |
< 0.05 |
375.60 ± 118.60 |
502.70 ± 98.10 |
< 0.05 |
| Circularity index° |
0.30 ± 0.10 |
0.62 ± 0.11 |
< 0.005 |
0.20 ± 0.06 |
0.60 ± 0.11 |
< 0.0001 |
| Complexity index (1/μm)& | 0.30 ± 0.03 | 0.19 ± 0.02 | < 0.0001 | 0.40 ± 0.08 | 0.20 ± 0.03 | < 0.0001 |
* Feret diameter: longest axis length.
° Circularity index: Feret diameter/short axis length.
& Complexity index: perimeter/area (1/μm).