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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: Nature. 2011 Aug 31;478(7367):97–102. doi: 10.1038/nature10406

Figure 1. Effect of the 16p11.2 duplication on BMI and head circumference.

Figure 1

Z-score values of BMI (top row) and head circumference (bottom row) of 16p11.2 duplication carriers stratified by gender and age group. The most severe effect is observed in children 0–5 years of age. Abscise: age groups in years. Boxplots represent the 5th, 25th, median, 75th and 95th percentile for each age group. Light grey and dark grey background represent −2 and −3 SD respectively, which correspond to the WHO definition of moderate and severe underweight4. BMI is decreased in adolescent and adult females.