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. 2013 Apr 26;8(4):e62342. doi: 10.1371/journal.pone.0062342

Table 2. Censoring information for survival study: animal n by cause of death/euthanasia for SOD1 Tg mice.

SOD1 Tg mice only
Cause of death/euthanasia Vehicle Erlotinib Total Censored?
Loss of righting reflex (within 15s) 14 25 39 no
Loss of 20% body weight (from peak weight) 8 5 13 no
Both the above 5 6 11 no
Found dead (possible bad injection)* 15 (3F,12M) 7 (4F, 3M) 22 yes
Found dead (close to euthanasia)** 4 3 7 no
Euthanized due to injury (skin lesions) 0 1 (M) 1 yes
Lost >20% peak body weight but no other critical signs 0 1 (F) 1 yes
Total censored 15 (3F,12M) 9 (5F, 4M) 24
Total uncensored 31 (19F,12M) 39 (19F,20M) 70
GRAND TOTAL 46 (22F,24M) 48 (24F,24M) 94

F: female; M: male.

*

mouse was above critical weight and had normal righting reflex.

**

mouse had already shown first signs of loss of righting reflex.