Table 2. List of residues at the binding interface of Hb-Hp complex.* .
| Residue | Frequency | Residue | Frequency |
| Hemoglobin α | Haptoglobin β | ||
| Val1 | 8 | His5 | 9 |
| Met76 | 9 | Leu6 | 10 |
| Pro77 | 7 | Asp7 | 9 |
| Pro95 | 10 | Ala8 | 10 |
| Lys99 | 7 | Lys9 | 9 |
| Lys127 | 10 | Thr61 | 9 |
| Ala130 | 8 | Tyr63 | 9 |
| Ser131 | 9 | Val64 | 10 |
| Thr134 | 10 | Arg125 | 9 |
| Val135 | 10 | Asn128 | 9 |
| Ser138 | 10 | Phe129 | 10 |
| Lys139 | 10 | Lys130 | 10 |
| Tyr140 | 10 | Phe131 | 10 |
| Arg141 | 10 | Thr132 | 9 |
| Asp133 | 9 | ||
| Hemoglobin β | His134 | 10 | |
| Tyr35 | 10 | Glu153 | 8 |
| Pro36 | 9 | Ser155 | 8 |
| Trp37 | 10 | Thr156 | 10 |
| Phe41 | 7 | Val157 | 10 |
| Glu90 | 9 | Pro158 | 10 |
| Asp99 | 7 | Lys160 | 10 |
| Pro100 | 7 | Lys161 | 8 |
| Glu101 | 10 | Lys218 | 10 |
| Leu105 | 9 | ||
| His143 | 9 | ||
| Lys144 | 10 | ||
| Tyr145 | 10 | ||
| His146 | 10 |
*
Residues in bold text are those also found in the Hb-Hpβ complex.