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. 2013 Apr 26;8(4):e62996. doi: 10.1371/journal.pone.0062996

Table 3. List of residues at the binding interface of Hb-Hpβ complex. * .

Residue Frequency Residue Frequency
Hemoglobin α Haptoglobin β
 Val1 8 Ile1 8
 Met76 8 Leu2 10
Asp94 7 Gly4 7
 Pro95 10 His5 10
Val96 7 Leu6 10
 Lys99 10 Asp7 10
 Lys127 8 Ala8 10
 Ala130 9 Lys9 10
 Ser131 10 Ser11 9
 Thr134 10 Val64 7
 Val135 8 Glu99 8
 Ser138 10 Arg125 10
 Lys139 9 Lys130 10
 Tyr140 8 Phe131 10
 Arg141 10 Thr132 10
Asp133 10
Hemoglobin β His134 10
 Pro36 8 Lys136 10
 Trp37 10 Tyr137 9
Arg40 10 Pro158 8
 Phe41 10 Lys160 10
Asp94 8 Lys161 7
His97 10 Gln186 10
 Asp99 10 Glu187 10
 Pro100 10 Asp188 7
 Glu101 10 Tyr191 10
Asn139 10 Lys218 8
Ala142 9 Val222 8
 His143 10
 Lys144 10
 Tyr145 10
 His146 10
*

Residues in bold text are those also found in the Hb-Hp complex.