Figure 2. Expression or miR-132 and miR-212 in the CNS.

Total RNA was isolated from the cortex (A) or cerebellum (B) of wild-type (+/+), miR-132/212 floxed (fl/fl), miR-132/212 knockout (−/−) mice. The levels of mature miR-132 and miR-212 were determined by qPCR. For the cortex samples, the levels of the mRNAs for p250Gap, MeCP2 and p300 were also determined (C). Error bars represent the standard deviation of 5 mice. A p value (students t-test) of <0.05 is indicated by * and <0.01 by **.