Figure 2. Screening for mitotic inhibitor using zebrafish embryo.

A. Embryos were incubated with compounds in multi well plates and visualized under a dissection microscope. A compound was considered as positive if division of all three embryos in the well was inhibited. B. A normal embryo after 4 hours of development. C. An embryo with cell division inhibited at 1 cell stage when an active inhibitor was present even after 4 hours of development.