Table 2. Selected differentially expressed gene groups in SKOV3 cells upon RUNX1 knock-down.

Upregulated genes
apoptosis	AMID, APG12L, EMP1, FAS, GADD45A, GULP1, HTATIP2, IER3, IL18, IL1A, INHBA, ITGB2, TC3, TLR2, TNFAIP3, TNFRSF21
cell cycle	CCNB1, CDCA1, CKS2, FGF5, IL1B, IL8, SFN, TGFB2
cell adhesion	ASAM, CD34, CD44, CDH18, CLDN1, CLDN3, FBLN2, ICAM2, LAMC2, NELL2, PKP2A, PODXL, TGFBI
cell growth and proliferation	ABLIM3, ADAMTS1, ANLN, AREG, C14orf151, CCNA1, CXCL1, EFEMP1, EGFL3, EPLIN, KLF4, KRT19, KRT7, KRTHA3A, LUM, NUDT6, TUBA1, TUBA2,. TUBGCP3, TUFT1
regulation of transcription	AML1a, ATF3, BACH1, C10orf48, C21orf7, E2F7, ESRRA, FLI1, FLJ20449, FLJ37649, FOSL1, FOXQ1, GATA5, GATA6, HPF1, IER5, IFI16, IRF2, KLF8, MYEF2, NFKB1, NFKBIE, NT5C, OVOL2, POLR1D, SCML1, SP5, TIGD2, VGL-3, ZNF311, ZNF582
signal transduction	ADRB2, ADORA2B, ANGPT2, ADM, DUSP10, RHDE, INPP1, RAB39B, RALA, OXTR, NMU, APBB1IP, PPP1R1B, APBB1IP, INPP4B, PDE1C, PDE10A, LGR7, GPRC5A, GPRC5B, GPR74, GPR110, STC2, WNT10A, DEPDC1, SH2D4A, ARF7, RAB32, ARL4, RHOJ, RAB34, RHOD, DLGAP1, DKK1, MDK, BIRC3, CD97, EDN1, FGF2, OPHN1, WISP2, PSG2, CEACAM7, EFCAB1, HRASLS, HRASLS2, RHOBTB3, S100A3, S100A4
metabolism	HERC4, BC015514, BC047030, CA2, LDLR, ALDH1A3, RBMS3, AGPAT4, ME3, PAPSS2, AADAC, CA12, CDA, CPM, GLUL, MEST, CD73, PLAG1, PTPRB, UAP1, UGCG, DDO, UCHL1, GDA, GALNT3, VNN1, DHRS3, GCHFR, H1F0, BCAT1, TFPI, EBP, ZNF185, GLUD2, DIO2, (NMNAT2, ATP11A, TMLHE, FLJ11088, NANS, SERPINB1, LOXL4, PPP1R14A, GALM, OSBPL3, RAD52B, PTE2B, ABHD7, NMNAT3, LOC201164, UPP1, NAV2, CMAH
transport	AP3S1, ATOX1, CFTR, CNGA1, COL17A1, COL4A4, CTHRC1, CYB5R4, CYP24A1, CYP4V2, FLJ22028, FOLR3, GJA1, IL4I1, KCTD4, LOC203427, LTF, NNT, RBP7, SLC22A3, SLC2A6, SLC39A8, SYTL3, Sytl4, TICAM2, TMED7, TRPC6, TRPM2, UNC13D

Downregulated genes
cell cycle	APC2, BCL2, KIAA1036, LZTS1, MATK, MTSS1, SEPT4, SEPT6
cell adhesion	AB208934, ADAM23, AK021957, BAI1, BBS2, CDH1, CDH16, CDH22, CDH6, CLDN23, COL12A1, COL5A1, COL6A2, COL8A1, DLL1, FBLN5, FEZ1, FLRT3, FN1, GP1BB, GPR56, HMCN1, ITGB3, JAM2, KITLG, LAMC3, MBP, NID2, NLGN4X, NLGN4Y, PCDHA1, PCDHB11, PCDHB16, PCDHB2, PCDHB5, PCDHB6, PCDHB8, PCDHB9, RET, ROBO1, S70348, SCARF2, TLN2, TRO
cell growth and proliferation	AKR1C3, AL390129, APEG1, AR, BAI1, BST2, CD40, ChGn, CHRD, CNN1, CREG1, CSPG2, CYR61,, DMD, EPB41L1, FGFR2, FGFR3, FNDC1, FNDC5, GRN, IGFBP2, KIF12, KITLG, LCE1B, LTBP1, LTBP3, LTBP4, MYO10, NDRG2, NDRG4, NRP1, ODF1, P8, PDGFD, RUNX3, SPTBN5, SSTR2, TNFRSF11B, TRIB1, TSPAN1, TUBB3, ZFP36L2
regulation of transcription	BAPX1, BRACE3032537, CSEN, CUTL2, DLX5, DTX1, EBF3, EGR1, EIF4EBP2, EMX2, EOMES, FLJ13298, GCL, GLI1, GSC, HEXIM1, HEXIM2, HEY2, HLF, HOXA9, HOXC8, HSPB1, ID2, ID4, IRX3, IVNS1ABP, KIAA0518, LEF1, LHX6, LMO2, LOC392152, MAFB, MEIS1, NANOS1, NFATC1, NKX6-2, NPAS2, NR2F1, NR2F2, NR4A1, NUDT21, ONECUT2, OVOL1, RARB, RNASE4, RUNX1, SALF, SALL1, SALL2, SHOX2, SNAI1, TBL1XR1, TFCP2L1, THRA, TLE2, TLX2, TSC22D1, ZFHX2, ZFHX4, ZIM3, ZNF114, ZNF219, ZNF452, ZNF537, ZNF556, ZNF6
signal transduction	ANXA4, ANXA6, ARF4L, ATRNL1, AXIN2, BAI2, BMP4, BMP6, BMP7, CXXC4, D4S234E, DIRAS1, DKFZp761O1810, EYA2, GFRA1, GHR, GNG3, GNG4, GPM6B, GPR124, GRB14, GRCA, ITPKA, INHBB, KCNH2, KREMEN2, LPHN3, MC1R, M1, MPP1, MPP3, MMP7, MMP11, NUDT11, PDE3B, PDE7A, PDE8B, PIK3R3, RAB15, RASGEF1A, RASGRP3, RASIP1, RASSF2, RASSF5, RGS9, RHOBTB1, RRP22, RTN4R, SEMA4G, SFRP1, SH3MD1, SNTB1, SPARC, STMN3, TNNI3, VAV3, WNT3A, WNT5A, WNT6, ZD52F10
metabolism	ABLIM2, ACSL5, ADPN, ADSSL1, AK5, AKR1B1, AKR1B10, AKR1C1, ALDH2, ANK3, APOC1, ARG2, ASRGL1, AUH, C6orf68, CFTR/MRP, CHST6, CILP, CTONG3005648, DHDH, DHRS6, DNM3, DPYSL2, DPYSL4, DSCR1L1, EEF1A2, ENPP5, FMNL1, GAA, GALNAC4S-6ST, GALNT14, GAMT, GLS, GLT8D2, GPT2, GSTT2, GUCY1A2, GUCY1B3, H2AFY2, H3F3A, HGD, HMOX1, IMAGE:3952485, KHK, KIAA1727, LARGE, LOC389129, MAN1A1, MAN1C1, MARLIN1, MMP1, MMP15, MMP19, MMP7, MOXD1, NEIL1, NP, NT2NE2000392, OGDHL, PAMCI, PFKM, PGM2L1, PHGDH, PKM2, PPAP2B, PPP1R1A, PROS1, PTGS1, QPRT, RKHD3, SLC27A2, SMARCD3, SOD3, SRrp35, ST3GAL5, TDO2, TEKT1, TM7SF2, TMEM54, TMSL8, UGT1A6, UGT1A8
transport	ABC1, ABCC5, ACCN2, AMBP, AMPH, APOE, Apo-E, ARL7, ATP10A, ATP1B2, ATP1B4, ATP8B2, CACNA1G, CACNB4, CHRNA3, COL23A1, COLEC12, COX4I1, CYB5, CYP26A1, DKFZp761K0912, DNM1, ELMOD1, EMID1, FDXR, FLJ10847, FLJ31196, FXYD2, GFOD1, GJB2, HEMBA1007301, IBRDC2, ICA1, ITPR1, KCNC1, KCNE3, KCNJ16, KCNJ4, KCNJ8, KCNMA1, KCNQ1, KCNS3, KCTD12, LCN2, LRP4, MRAS, NBEA, NOX4, NUP93, PDIA2, PLACE1008629, RAB3B, RAB6B, RBP4, RIMS2, RIMS3, SCAMP5, SLC6A6, SLC10A4, SLC12A5, SLC26A10, SLC2A11, SLC40A1, SNIP, SYT17, SYTL1, SYTL2, TRPM4