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MMP-9 expression was up-regulated by S100A7 cDNA transfection and down-regulated by S100A7 siRNA transfection. A, Western blot analysis of MMP-9 protein expression in transfected MDA-MB-468 cells. B, MMP-9 activity assay showing that MMP-9 was up-regulated by S100A7 cDNA transfection and down-regulated by S100A7 siRNA transfection. Each bar represents mean ± SE (n = 3); *, P <0.01. MMP-9, matrix metalloproteinase 9.
