Table 4.
Overview of selected literature
|
Ref. no. |
Cell source |
Sorting |
Selective culture |
Clonality |
Potency |
||
|---|---|---|---|---|---|---|---|
| Adipogenic | Osteogenic | Chondrogenic | |||||
| [2] |
degenerated IVD endplate |
no |
agarose |
no |
+/- |
+ |
+ |
| [3] |
degenerated AF and NP |
CD 133 +/- |
no |
no |
+/- |
+/- |
+ |
| [6] |
degenerated NP |
no |
no |
no |
- |
+ |
+ |
| [8] |
articular cartilage |
no |
agarose |
yes (cluster) |
+/- |
+/- |
+/- |
| |
(ACI surgery) |
|
|
|
|
|
|
| [26] |
normal articular cartilage |
no |
TGFb1, FGF-2, PDGF-BB |
yes (n = 20 clones) |
20% of clones |
25% of clones |
60% of clones |
| |
|
|
|
2 A/O/C |
|
|
|
| [26] |
normal articular cartilage |
no |
no |
yes (n = 7 clones) |
57% of clones |
28% of clones |
57% of clones |
| |
|
|
|
1 A/O/C |
|
|
|
| [28] |
articular cartilage (knee surgery) |
no |
fibronectin coating, osteogenic differentiation in pellet culture |
yes |
+/- |
+ |
+ |
| [29] |
OA cartilage |
CD166 +/- |
no |
no |
+/- |
+ |
+ |
| [58] |
articular cartilage |
no |
no |
yes (n = 53) |
+/- |
+ |
+ |
| |
(ACI surgery) |
|
|
17 A/O/C |
|
|
|
| [59] |
OA cartilage |
no |
no |
|
not done |
- |
+ |
| [60] |
normal, OA cartilage |
CD 155+/CD166+ |
no |
no |
+/- |
+ |
+ |
| [61] |
normal, OA cartilage |
Hoechst dye 33342 |
no |
no tissue immunostaining |
- |
+/- |
+ |
| presented study | normal, OA cartilage, IVD | W5C5 +/-W8B2 +/- | no | no | +/- | +/- | + |
+/- = differentiation either only by gene expression or only spotty distribution in Oil Red staining or mineral deposition or chondrogenesis.