Table 4.
Cox regression for association between mortality of all-cause and parameters of mineral metabolism
|
Factors |
Model 1 |
Model 2 |
Model 3 |
|---|---|---|---|
| All cause mortality HR (95%CI) FGF23 | age | age, eGFR, phosphate | age, BMI, eGFR, albumin, calcium, phosphate, (PTH, FGF23 or 25D as appropriate), smoking, diabetes, hypertension, prevalent cancer, prevalent CVD |
| Q1 |
ref |
ref |
ref |
| Q2 |
1.03 |
0.96 |
0.86 |
| (0.75 - 1.40) |
(0.72 - 1.36) |
(0.60 - 1.25) |
|
| Q3 |
0.93 |
0.85 |
0.82 |
| (0.67 - 1.29) |
(0.61 - 1.38) |
(0.58 - 1.16) |
|
| Q4 |
1.27 |
0.99 |
1.13 |
| (0.94 - 1.73) |
(0.71 - 1.38) |
(0.80 - 1.59) |
|
| Log10FGF23/(1-SD) |
1.09 |
1.01 |
1.02 |
| 0.97-1.22 |
0.89-1.14 |
0.89-1.17 |
|
| Log PTH/(1-SD) |
1.16 * |
1.09 |
1.04 |
| (1.03 - 1.30) |
(0.97 - 1.22) |
(0.92 - 1.18) |
|
| 25D/10 nmol/L |
0.90 ** |
0.90 ** |
0.91 ** |
| (0.85 - 0.95) |
(0.85 - 0.95) |
(0.87 - 0.97) |
|
| CVD mortality HR (95%CI) |
|
|
|
| Q1 |
ref |
ref |
ref |
| Q2 |
1.76 * |
1.66 |
1.67 |
| (1.04 - 2.96) |
(0.98 - 2.83) |
(0.97 - 2.88) |
|
| Q3 |
1.15 |
1.00 |
0.80 |
| (0.64 - 2.07) |
(0.55 - 1.82) |
(0.42 - 1.51) |
|
| Q4 |
1.86 * |
1.30 |
1.37 |
| (1.09 - 3.17) |
(0.73 - 2.32) |
(0.74 - 2.51) |
|
| Log10FGF23/(1-SD) |
1.43 ** |
1.26* |
1.26 |
| (1.18 - 1.73) |
(1.01 - 1.56) |
(0.99 - 1.59) |
|
| Log10PTH/(1-SD) |
1.26 * |
1.13 |
1.02 |
| (1.04 - 1.52) |
(0.94 - 1.37) |
(0.84 - 1.23) |
|
| 25D/10 nmol/L |
0.92 * |
0.91 * |
0.94 |
| (0.84 - 1.00) | (0.84 - 0.99) | (0.86 - 1.02) | |