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A-B) One of the biopsies taken during REAC-TO treatment. C) Skin. Area of moderate cutaneous excoriation. The underlying dermis present mixed inflammatory cells and some eosinophilic granular cells (HE, 10X). D) Skin 3 day post-treatment. The upper dermis present numerous fibroblast and abundant fibrous matrix (HE, 10X) E) Skin 7 day post-treatment. Fibroplasias in the upper dermis (HE, 10X). Serial 4 μm sections were stained with haematoxylin and eosin (HE).
