Table 2.
Characteristics of HCC and comparison of tumor characteristics among viral-HCC vs. viral marker negative HCC
| |
ALL HCC cases |
Comparison of viral-HCC vs. viral marker negative HCC |
||
|---|---|---|---|---|
| |
n = (645) |
|
|
|
| Mean ± SD/n (%) | Viral HCC (n = 546) | Viral marker negative HCC(n = 99) | P value | |
|
Duration between diagnosis of cirrhosis & HCC(months) |
|
|
|
|
| 00 |
291(45.1) |
226(41.4) |
65(65.7) |
<0.001 |
| 1-55 |
243(37.7) |
219(40.1) |
24(24.2) |
|
| >55 |
111(17.2) |
101(18.5) |
10(10.1) |
|
|
Mode of diagnosis |
|
|
|
|
| On screening |
53(8.2) |
52(9.5) |
1(1.0) |
0.001 |
| Incidental |
57(8.8) |
44(8.1) |
13(13.1) |
|
| Symptomatic |
535(82.9) |
450(82.4) |
85(85.9) |
|
|
Stage of HCC |
|
|
|
|
| Non-advance |
240(37.2%) |
222(40.7) |
18(18.2) |
<0.001 |
| Advance |
405(62.8%) |
324(59.3) |
81(81.8) |
|
|
Macroscopic types |
|
|
|
|
| Solitary |
246(38.1) |
213(39.0) |
33(33.3) |
0.04 |
| Paucifical (≤ 3 nodules) |
259(40.2) |
223(40.8) |
36(36.4) |
|
| Multifocal(>3 nodules) |
96(14.9) |
79(14.5) |
17(17.2) |
|
| Massive/infiltrative |
44(6.8%) |
31(5.7) |
13(13.1) |
|
|
Maximum tumor size (cm) |
|
|
|
|
| < 5 |
359(55.65) |
326(59.7) |
33(33.3) |
<0.001 |
| 5-10 |
213(33.02) |
173(31.7) |
40(40.4) |
|
| >10 |
73(11.31) |
47(8.6) |
26(26.3) |
|
|
Hepatic lobes |
|
|
|
|
| Left |
81(12.6) |
69(12.6) |
12(12.1) |
0.98 |
| Right |
387(60) |
327(59.9) |
60(60.6) |
|
| Both |
177(27.4) |
150(27.5) |
27(27.3) |
|
|
PVT |
|
|
|
|
| No |
429(66.5) |
359(65.8) |
70(70.7) |
0.33 |
| Yes |
216(33.5) |
187(34.2) |
29(29.3) |
|
|
Extra hepatic spread |
|
|
|
|
| No |
560(86.8) |
479(87.7) |
81(81.8) |
0.12 |
| Yes | 85(13.2) | 67(12.3) | 18(18.2) | |