Table 4.
Functional enrichment from DAVID analysis
| Category | Term | Count | % | P | Fold Enrichment | FDR |
|---|---|---|---|---|---|---|
| GOTERM_BP_FAT (Biological process) |
GO:0008285 negative regulation of cell proliferation |
14 |
5.1 |
6.77 E-04 |
3.1 |
1.12 |
| GO:0006953 acute-phase response |
5 |
1.8 |
1.58 E-03 |
9.8 |
2.60 |
|
| GO:0008202 steroid metabolic process |
9 |
3.3 |
4.16 E-03 |
3.5 |
6.70 |
|
| GO:0001960 negative regulation of cytokine-mediated signaling pathway |
3 |
1.1 |
4.23 E-03 |
29.5 |
6.81 |
|
| GO:0042127 regulation of cell proliferation |
20 |
7.3 |
5.03 E-03 |
2.0 |
8.04 |
|
| GO:0010038 response to metal ion |
7 |
2.5 |
5.92 E-03 |
4.3 |
9.40 |
|
| GOTERM_ CC_FAT (Cell compartment) |
GO:0005929 cilium |
10 |
3.6 |
3.26 E-05 |
6.2 |
0.04 |
| GO:0030286 dynein complex |
6 |
2.2 |
5.81 E-05 |
14.1 |
0.07 |
|
| GO:0005615 extracellular space |
22 |
8.0 |
1.16 E-04 |
2.6 |
0.15 |
|
| GO:0005930 axoneme |
6 |
2.2 |
1.46 E-04 |
11.7 |
0.19 |
|
| GO:0044421 extracellular region part |
26 |
9.5 |
3.26 E-04 |
2.2 |
0.42 |
|
| GO:0042995 cell projection |
21 |
7.6 |
4.05 E-04 |
2.4 |
0.52 |
|
| GO:0005856 cytoskeleton |
31 |
11.3 |
1.63 E-03 |
1.8 |
2.08 |
|
| GO:0005875 microtubule associated complex |
7 |
2.5 |
1.70 E-03 |
5.5 |
2.16 |
|
| GO:0044430 cytoskeletal part |
23 |
8.4 |
3.48E-03 |
1.9 |
4.39 |
|
| GO:0035085 cilium axoneme |
4 |
1.5 |
3.55 E-03 |
12.8 |
4.48 |
|
| GO:0005576 extracellular region |
39 |
14.2 |
4.51 E-03 |
1.6 |
5.65 |
|
| GOTERM_MF_FAT (Molecular Function) |
GO:0003777 microtubule motor activity |
6 |
2.2 |
2.95 E-03 |
6.1 |
4.03 |
| GO:0005509 calcium ion binding |
23 |
8.4 |
2.98 E-03 |
2.0 |
4.07 |
|
| UP_TISSUE |
Lung |
63 |
22.9 |
6.08 E-06 |
1.8 |
0.01 |
|
Testis |
80 |
29.1 |
2.59 E-03 |
1.3 |
3.06 |
|
|
Trachea |
13 |
4.7 |
7.16 E-03 |
2.4 |
8.26 |
|
| Plasma | 11 | 4.0 | 7.45 E-03 | 2.7 | 8.58 |
The most enriched GO terms found following submission of our gene list to the DAVID functional annotation tool, showing categories and GO terms enriched, number and percentage of gene lists genes represented in each enriched category, significance level (P), fold enrichment and false discovery rate (FDR).