. 2013 Mar 28;14(1):38. doi: 10.1186/1465-9921-14-38

Table 7.

Differentially expressed genes common to two or more of six comparable studies of CF related gene expression

Gene list	Regulated genes shared with current study (Clarke)
Zabner et al., 2005	UP: ACAA2, CDKN2B.
Zabner et al., 2005	DOWN:IGFBP2.
Wright et al., 2006	UP: C9orf3, KRT14.
Wright et al., 2006	DOWN:CYP24A1, HLA-DQA1, SAA4.
Virella-Lowell et al., 2004	UP: CAV1, CCNE2.
Virella-Lowell et al., 2004	DOWN: CLGN, ENO2, EPB41L3, GPX3, TIMP4.
Verhaeghe et al., 2007	UP:BCL2A1, G0S2, IL1B, MMP1, RGS2.
Verhaeghe et al., 2007	DOWN: CKB, CRIP1, CYP24A1, DNALI1, FHL1, GSTT1, IGFBP2.
Ogilvie et al., 2011	UP:BCL2A1, G0S2, IL1B, IL1R2, LCP2, NDRG1, RGS2, RNF149, TCN1.
Ogilvie et al., 2011	DOWN: PROS1, SCGB1A1, SPAG8.
All shared genes (six studies combined)
UP (n = 75): ACAA2, AGL, AKR1C1, ANXA8L2, BCHE, BLOC1S1, BTBD3, C9ORF3, CAPG, CAV1, CCL20, CCNE2, CD24, CD83, CDKN2B, CLGN, CSF3, DDX3Y, ELK3, FOLR1, FOLR3, FOXG1, GCA, GFPT2, HCLS1, HIST1H1C, HMOX1, HPCAL1, HSPB11, IFIT1, IFIT3, IFITM1, IL1R2, IL7R, ISG15, KCTD12, KRT14, KRT81, LCP2, LITAF, LYPD1, MLF1, MMP1, MRPL28, MX2, NCF1, NDRG1, NET1, PLAU, PLAUR, PLTP, PRSS3, PSG9, PTPN13, RAC2, RAGE, RNF149, RPA3, SEMA3B, SERPINA3, SERPINF1, SLITRK5, SOD2, SULT1A3, TCF15, TCIRG1, TCN1, TXNIP, BCL2A1, G0S2, IL1B, NCF2, PLAT, PTGS2, RGS2.
DOWN (n = 114): ACTA2, ADAR, ALDH1A1, ANKRD1, ASNS, ASS1, BEX4, BST2, BTG1, C5ORF13, CALD1, CAP1, CCL20, CD164, CFB, CGREF1, CKB, CLGN, COL8A1, COL9A3, CRIP1, CSTA, CXCR4, CYP51A1, DDB2, DDIT4, DNALI1, DSP, DSTN, DYNLT1, EDNRA, EFEMP1, EIF4A2, ENO2, EPB41L3, EPS8, F3, FBLN5, FCGBP, FHL1, GABRP, GCH1, GINS1, GPNMB, GPR1, GPX3, GSTT1, GZMB, HCP5, HES1, HLA-B, HLA-DQA1, HLA-DRA, HLA-DRB1, HLA-F, HLA-G, HMGCS1, HSPB1, HTRA1, ID1, IFI16, IFITM1, IFRD1, IGFBP7, IL32, KCNN4, KIT, KLRK1, KRT15, LCN2, LGALS3BP, LOX, MGAM, MSC, NID2, NPR3, NTS, PGD, PNMA2, PPP1R3C, PROS1, RASGRP1, RND3, RUNX3, SAA4, SC5DL, SCGB1A1, SERPINB3, SERPINB4, SGK1, SLC2A3P1, SNAPC1, SPAG8, STAC, STAT4, TES, TFPI, THBD, TIMP4, TPBG, TRIB2, TWIST1, VDAC1, ZNF643, CTSC, CYP24A1, IFI27, IGFBP2, IGFBP3, NAMPT, PRSS23, SEL1L3, TMSB4X, TRIM22.

Genes shared between two other lists and the present study (ie, differentially expressed in the same direction with respect to CF-vs.-Control cells) are underlined. The lower panel shows genes shared between two or more studies when all six studies are combined. Genes shared with present study (see upper panel) are shown in italics, genes shared between three studies are underlined.