Table 9.
Small molecular signature for native CF airway epithelial cells
| Upregulated | |
|---|---|
|
ALOX5AP |
arachidonate 5-lipoxygenase-activating protein; #241 |
|
BCL2A1 |
BCL2-related protein A1; #597 |
|
CXCR4 |
chemokine (C-X-C motif) receptor 4; #7852 |
|
FCGR3A |
Fc fragment of IgG, low affinity IIIa, receptor (CD16a); #2214 |
|
FOS |
FBJ murine osteosarcoma viral oncogene homolog; #2353 |
|
G0S2 |
G0/G1switch 2; #50486 |
|
GCNT3 |
glucosaminyl (N-acetyl) transferase 3, mucin type; #9245 |
|
HIST1H1C |
histone cluster 1, H1c; #3006 |
|
HIST1H2BK |
histone cluster 1, H2bk; #85236 |
|
IL1B |
interleukin 1, beta; #3553 |
|
IL1R2 |
interleukin 1 receptor, type II; #7850 |
|
LITAF |
lipopolysaccharide-induced TNF factor; #9516 |
|
OSM |
oncostatin M; #5008 |
|
PLEK |
pleckstrin; #5341 |
|
PTGS2 |
prostaglandin-endoperoxide synthase 2; #5743 |
|
RGS2 |
regulator of G-protein signaling 2, 24 kDa; #5997 |
|
S100A8 |
S100 calcium binding protein A8; #6279 |
|
S100A9 |
S100 calcium binding protein A9; #6280 |
|
SERPINA3 |
serpin peptidase inhibitor, clade A, member 3; #12 |
|
TCN1 |
transcobalamin I (vitamin B12 bp, R binder family); #6947 |
|
TPM4 |
tropomyosin 4; #7171 |
|
Downregulated | |
|
CAPS |
calcyphosine; #828 |
|
CHST9 |
carbohydrate (N-acet.gal.am. 4–0) sulfotransferase 9; #83539 |
|
DNALI1 |
dynein, axonemal, light intermediate chain 1; #7802 |
|
MAOB |
monoamine oxidase B; #4129 |
|
NELL2 |
NEL-like 2 (chicken); #4753 |
|
PPP1R16A |
protein phosphatase 1, regulatory subunit 16A; #84988 |
|
PROS1 |
protein S (alpha); #5627 |
|
PTGFR |
prostaglandin F receptor (FP); #5737 |
| RAGE | MOK protein kinase; #5891 |
Regulated genes shared between our study and reanalysed lists from another recent study [19]. Gene symbols, descriptions and Entrez IDs (#) are shown.