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Plasma ACTH (P<0.05) and corticosterone (cort)(P<0.05) response to an acute 30 min restraint stress challenge was enhanced in animals that received the GABA-A receptor agonist muscimol into the posterior-medial BNST. Muscimol microinjection into the posterior-medial BNST also increased c-fos expression in the PVN of the hypothalamus(P<0.05). Data are shown as mean±SEM.*P<0.05 versus saline.
