Fig. (4).
Plasma corticosterone response to an acute 30 min restraint stress challenge in animals that received bilateral microinjection into the anterolateral BNST of vehicle (100nL), the β-adrenoceptor antagonist propranolol (10nmol/100nL) or a cocktail containing the selective α1-adrenoceptor antagonist WB4101 (10nmol/100nL) and the selective α2-adrenoceptor antagonist RX821002 (10nmol/100nL) (WB+RX). The response in animals treated with the cocktail of WB+RX was enhanced (P<0.05), whereas propranolol microinjection did not affect plasma corticosterone response (P>0.05). Circles represent the mean and bars the SEM; n=12-14. *P<0.05 versus vehicle group, two-way ANOVA followed by Bonferroni’s post hoc test.