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. 2013 Mar;11(2):209–217. doi: 10.2174/1570159X11311020007

Fig. (1).

Fig. (1)

Depressor effect of brain ACE2-Ang-(1-7)-Mas axis and the related mechanisms. Abbreviations: ACE, Angiotensin converting enzyme; Ang I, Angiotensin I; Ang II, Angiotensin II; Ang-(1-7), Angiotensin-(1-7); AT1R , Angiotensin II type 1 receptor; AT2R , Angiotensin II type 2 receptor; BK, Bradykinin; eNOS, Endothelial nitric oxide synthase; IKv, Delayed rectifier K+ current; IL-1β, Interleukin-1β; IL-6, Interleukin-6; MDA, Malondialdehyde; NE, Norepinephrine; nNOS, Neuronal nitric oxide synthase; NO, Nitric oxide; SOD, Super oxygen dehydrogenises; TNF-α, Tumour necrosis factor–α.