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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: Psychopharmacology (Berl). 2013 Jan 25;227(2):307–320. doi: 10.1007/s00213-013-2981-4

Figure 4. Intracerebroventricular microinjection of cocaine in AM and PM fed rats.

Figure 4

Cocaine was microinjected into the lateral ventricle of AM-fed (filled circles) and PM-fed (open circles) food-restricted rats. Shown are mean ±SEM percent change in two measures of reward threshold, M-50 (top panel) and X-intercept (middle panel), and maximum reinforcement rate (bottom panel) as a function of dose. *p<0.05, ***p<0.001 compared to the 0.0 (vehicle) dose.