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Effect of estrogens on size of IR-induced cardiac infarction. A, representative female rat heart sections following IR injury, with reperfusion under control or in the presence of BPA or BPA plus E2 (all at 1 nM). TTC stained red area indicates viable tissue, pale-white regions (arrows) indicate infarction. B, infarction size (as a percentage of the whole heart) when exposed to various treatments during reperfusion. N = 7 – 11 hearts. Error bars are SEM. *: P < 0.05 vs control.
