Immunohistochemical analysis of FOXM1 expression in human thyroid tissue samples. Representative images of normal thyroid (NT), classic variant-PTC (CL-PTC), follicular variant-PTC (FV-PTC), PDC, and ATC biopsies stained with a rabbit polyclonal anti-FOXM1 antibody. Whole tissue cores (left, 10×) and zoom-in of areas present within these particular cores (center, 40× and right, 100×), illustrating the nuclear features and FOXM1 staining pattern, are shown. The NT, CL-PTC, and FV-PTC sections are negative for FOXM1, whereas the PDC and ATC sections disclose diffuse, medium/moderate (++), and high/ strong (+++) nuclear immunoreactivity respectively.