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. Author manuscript; available in PMC: 2014 Apr 15.
Published in final edited form as: Transplantation. 2013 Apr 15;95(7):908–915. doi: 10.1097/TP.0b013e318278d367

Table 1.

Average tacrolimus dose, whole blood and unbound trough concentrations during early-, mid-,and late-pregnancy as well as > 3 months postpartum

Early-
pregnancy		 Mid-
pregnancy		 Late-
pregnancy		 >3 Month
Postpartum
Dose-Norm alized (per 1 mg/day)
Tacrolim us Trough Concentrations
(ng/m L)		 0.8 ± 0.03 0.4 ± 0.1 0.8 ± 0.04 0.9 ± 0.5
Average Tacrolim us Dose (mg) 6.9 ± 2.5 9.3 ± 1.6 6.7 ± 3.3 5.6 ± 1.8
Average Tacrolim us Whole Blood
Trough Concentration (ng/mL)		 5.6 ± 4.1 4.0 ± 0.7 4.9 ± 2.4 4.4 ± 1.4
Average Tacrolimus Unbound Trough
Concentration (ng/m L)		 0.011 ±
0.008		 0.014 ±
0.007		 0.018 ±
0.010		 0.008 ±
0.003