Figure 1.

Influence of HDACi and DNMTi on viability of MHH-CALL-4. Incubation with vorinostat, decitabine, and azacytidine resulted in significant dose dependent reductions of cell viability whereas no reduction could be observed after incubation with valproic acid. Shown are mean values of absorbance ratio (absorbance of treated cells/absorbance of untreated cells) and standard deviation (n = 3 for vorinostat, n = 6 for valproic acid, n = 4 for decitabine and azacytidine, *p < 0.05, **p < 0.01, ***p < 0.005).