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. 2013 Apr 9;10(6):707–718. doi: 10.7150/ijms.5726

Fig 7.

Fig 7

Staurosporine inhibited autophagy and promoted apoptosis in PAB-treated L929 cells. A: PAB increased MDC positive staining, but was blocked by staurosporine. B: PAB increased the expression of Beclin 1 and LC3 II expression which marked autophagy, but was inhibited by staurosporine. C: PAB alone could not activate caspase 3, but combined with staurosporine caspase 3 was activated. D: In PAB-treated L929 cells, there was no DNA ladder, but combined with staurosporine DNA ladder appeared.