Figure 3.
Gene and protein feature of Pol η, and nonsense mutation spectrum of POLH gene and predicted proteins in XPV cells. The first part showed the 11 exons of POLH gene. The 713 amino-acid Pol η protein and the indicated conversed region or catalytic domain was shown in the second part. The third part showed the different predicted protein sizes associated to each nonsense mutation in the present study (red) and the reviewed XPV patients (black).