Schematic of the multi-scale model being developed within the AirPROM project; this illustration represents some of the model components required to represent an asthmatic patient. CFD, computational fluid dynamics; CT, computed tomography; DE, differential equation; FOT, forced oscillation technique; IgE, immunoglobulin E; IL, interleukin; MCh, methacholine; Th1, type 1 helper T cells.