Table 2.
Decrease of network efficiency and network flux, experimental results of each compound.
| Compounds | Inhibitiona | NE decrease % | NF decrease % | Combination of NE and NFd |
|---|---|---|---|---|
| Papaverine | 0.67 | 45.5 | 79.8 | 61.8 |
| Tirofibanb | 0.64 | 39.9 | 61.5 | 49.6 |
| Deoxycholic acid | 0.66 | 60.8 | 83.4 | 61.9 |
| Scutellarinc | 0.51 | 52.1 | 77.9 | 57.8 |
| Rhaponticinc | 0.65 | 42.8 | 65.6 | 47.3 |
| Dipyridamoleb | 0.60 | 41.8 | 74.1 | 55.6 |
| Chrysin | 0.68 | 47.9 | 75.5 | 65.6 |
| Wogonin | 0.67 | 55.6 | 68.7 | 58.8 |
| Rhein | 0.67 | 68.8 | 63.4 | 59.8 |
| Silybin | 0.73 | 56.6 | 96.6 | 71.6 |
| Danshensu | 0.57 | 32.2 | 43.4 | 38.3 |
| Quercetin | 0.67 | 47.9 | 89.7 | 76.7 |
| Chlorogenic acid | 0.54 | 34.6 | 37.9 | 38.6 |
| Icariinc | 0.65 | 53.4 | 62.0 | 55.6 |
| Quercitrinc | 0.57 | 41.8 | 60.0 | 50.1 |
| Baicalinc | 0.61 | 55.3 | 62.2 | 54.9 |
| Liquiritinc | 0.66 | 52.7 | 80.3 | 65.0 |
| Salvianolic acid C | 0.55 | 33.2 | 50.9 | 41.1 |
| Kaempferol | 0.63 | 50.4 | 71.9 | 60.3 |
| Salvianolic acid B | 0.53 | 25.0 | 22.8 | 23.9 |
| Picroside IIc | 0.51 | 24.7 | 68.8 | 44.6 |
aThe inhibition effect determined in the final concentration of tested compounds was 34 μM.
bTirofiban and dipyridamole are two approved drugs.
cThese seven molecules are glycoside compounds.
dCombination of NE decrease and NF decrease: the square root of the product of the percentage of NE decrease and the percentage of NF decrease.