Table 8.

The list of unique metabolites of DH.

Compound name	VIPa	P b	FNc
beta-Aminoisobutyric acid	1.47	0.02	−1.52
beta-D-Glucopyranose	1.81	0.00	−1.79
1-Naphthol	1.79	0.01	−1.64
Butanedioic acid	2.00	0.00	−1.76
D-Glucose	1.17	0.02	+1.24
Glycine	1.86	0.00	−1.87
L-Asparagine	1.62	0.01	−1.60
L-Lysine	1.68	0.02	−1.68
Urea	1.84	0.01	+1.80
1H-Indole-3-acetic acid	1.65	0.00	−1.91
1H-Indole-3-butanoic acid	1.65	0.01	−1.59
(R)-Mandelic acid	1.72	0.01	−1.67
Acetic acid	1.70	0.00	−1.89
Butyrate	1.71	0.00	−1.69
Creatinine	1.71	0.01	−1.66
1-Cyclohexenecarboxylic acid	1.90	0.00	−1.74
Aminolevulinic acid	1.61	0.00	−1.79
Glutaconic acid	1.73	0.01	−1.63
Pteridine	1.66	0.00	−1.72
Pyrazine	1.58	0.00	−2.10
Succinic acid	1.88	0.01	−1.71

  ^aVIP: variable importance in the project.

^b P value was obtained from Mann-Whitney test (ZHENGs compared to healthy control).

^cFN is fold change of mean ranks calculated by the Mann-Whitney test (ZHENGs compared to healthy control). “+” means upregulated, “−” means downregulated.