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Effect of CAPE treatment on EMT markers expression. PANC-1 cells exhibited a weak expression of E-cadherin and strong expression of vimentin by TGF-β stimulation. The downregulation of E-cadherin expression and upregulation of vimentin expression, markers of EMT, were reversed by CAPE treatment, but CAPE treatment did not reduce the expression levels of Smad 2/3 (at 24 h).
