Table 4.
Pathway pattern underlying core symptoms.
| Symbol | Pathway entry | Pathway description | count |
|---|---|---|---|
| 1a | hsa01100 | Metabolic pathways | 57 |
| 1b | hsa04151 | PI3K-Akt signaling pathway | 16 |
| 1c | hsa05200 | Pathways in cancer | 16 |
| 1d | hsa05010 | Alzheimer's disease | 13 |
| 1e | hsa04010 | MAPK signaling pathway | 13 |
| 1f | hsa05016 | Huntington's disease | 12 |
| 1g | hsa04510 | Focal adhesion | 12 |
| 1h | hsa00280 | Valine, leucine, and isoleucine degradation | 11 |
| 1i | hsa05012 | Parkinson's disease | 11 |
| 1j | hsa00190 | Oxidative phosphorylation | 11 |
| 1k | hsa04974 | Protein digestion and absorption | 10 |
| 1l | hsa03010 | Ribosome | 9 |
| 1m | hsa04810 | Regulation of actin cytoskeleton | 9 |
|
| |||
| 2a | hsa05012; hsa05016 | Parkinson's disease and Huntington's disease | 11 |
| 2b | hsa05010; hsa05012 | Alzheimer's disease and Parkinson's disease | 11 |
| 2c | hsa00190; hsa05010 | Oxidative phosphorylation and Alzheimer's disease | 11 |
| 2d | hsa00190; hsa05012 | Oxidative phosphorylation and Parkinson's disease | 11 |
| 2e | hsa05010; hsa05016 | Alzheimer's disease and Huntington's disease | 11 |
| 2f | hsa00190; hsa05016 | Oxidative phosphorylation and Huntington's disease | 11 |
|
| |||
| 3a | hsa00190; hsa05012; hsa05016 | Oxidative phosphorylation, Parkinson's disease, and Huntington's disease | 11 |
| 3b | hsa00190; hsa05010; hsa05016 | Oxidative phosphorylation, Alzheimer's disease, and Huntington's disease | 11 |
| 3c | hsa00190; hsa05010; hsa05012 | Oxidative phosphorylation, Alzheimer's disease, and Parkinson's disease | 11 |
| 3d | hsa05010; hsa05012; hsa05016 | Alzheimer's disease, Parkinson's disease, and Huntington's disease | 11 |
|
| |||
| 4a | hsa00190; hsa05010; hsa05012; hsa05016 | Oxidative phosphorylation, Alzheimer's disease, Parkinson's disease, and Huntington's disease | 11 |