Table 2.
The effect of ES and EE on the lipid profile of db/db mice.
| DM | ESL | ESH | EE | |
|---|---|---|---|---|
| Total cholesterol (mg/dL) | 375.11 ± 74.79 | 238.19 ± 86.42* | 247.29 ± 45.91* | 330.59 ± 21.17 |
| Triglyceride (mg/dL) | 180.24 ± 57.19 | 137.89 ± 35.77 | 113.93 ± 20.17* | 112.35 ± 29.75* |
| FFA (uEq/L) | 1412.78 ± 74.28 | 1080.16 ± 160.21* | 1190.08 ± 102.30 | 1072.38 ± 269.91* |
| Glucose (mg/dL) | 486 ± 21.53 | 397.8 ± 29.30* | 389.2 ± 21.24* | 315.0 ± 24.67* |
| Insulin (ng/mL) | 8 ± 1.8 | 2.81 ± 0.71* | 4.28 ± 1.29* | 3.56 ± 0.41* |
| HOMA-IR | 75.89 ± 13.64 | 36.49 ± 12.22* | 42.79 ± 15.95* | 33.5 ± 6.63* |
All values are expressed as the mean ± SEM. Six-week-old db/db mice were fed experimental diet containing none, 0.05–0.01 % E. senticosus (ES) extract, and 0.1% eleutheroside E (EE) for 5 weeks.
DM: diabetes mellitus group; ESL: 0.05% ES extract supplemented group; ESH: 0.1% ES extract supplemented group; EE: 0.003% eleutheroside E supplemented group.
*P < 0.05 when compared to the DM group using one-way ANOVA followed by post hoc Bonferroni's tests.