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. Author manuscript; available in PMC: 2013 Apr 29.
Published in final edited form as: J Steroid Biochem Mol Biol. 2004 Jan;88(1):101–110. doi: 10.1016/j.jsbmb.2003.11.002

Fig. 3.

Fig. 3

The effect of estradiol 17β (0.03–300 nM) in the presence or absence of high glucose on total activated MAP-kinase in VSMC and in E304 cells. Results are means of fluorometric assay of extracts from 2 to 3 incubates from 3 experiments and are expressed as the ratio between hormone-treated and control cells at a low glucose concentration. * P < 0.05; ** P < 0.01 for the comparison with control values at low glucose; # P < 0.05 for the comparison with control values at high glucose; and b P < 0.01 for the comparison between the effect of E2 with and without glucose. The statistical analysis was done by ANOVA as explained in the Materials and Methods section.