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. Author manuscript; available in PMC: 2013 Apr 29.
Published in final edited form as: J Immunol. 2008 Sep 15;181(6):4089–4097. doi: 10.4049/jimmunol.181.6.4089

FIGURE 4.

FIGURE 4

The inflammatory response associated with TH17 cell transfer is mediated by IL-17. TH17 cells were transferred to IL-17R KO mice and BALB/c controls that had been challenged with OVA 1 day before transfer. Mice were challenged with 50 μg of OVA per mouse for 3 consecutive days after transfer. BAL fluid differential and LH levels of cytokines and chemokines 24 h after the last airway challenge were determined. Levels of KC (A), G-CSF (B), and IL-6 (C) in the LH were determined by multiplex suspension cytokine array. BAL fluid neutrophils (D), and eosinophils (E) are expressed as cells/ml × 106. Data are graphed as mean ± SEM for n = 4 – 6; *, p < 0.05 compared with WT control.