TABLE 3.
Multivariate Predictors of CVD Mortality with Full Model and Stratified by Framingham Risk Score*
| Full Model |
Framingham Score < 10 (N = 396, 38 Deaths) |
Framingham Score 10–20 (N = 532, 72 Deaths) |
Framingham Score > 20 (N = 250, 62 Deaths) |
|||||
|---|---|---|---|---|---|---|---|---|
| RR (95% CI) |
P-value | RR (95% CI) |
P-value | RR (95% CI) |
P-value | RR (95% CI) |
P-value | |
| Clinical CVD | 2.2 (1.6–3.0) |
<0.001 | 2.9 (1.6–5.1) |
<0.001 | 2.6 (1.6–4.3) |
<0.001 | 1.9 (1.2–3.1) |
0.008 |
| Diabetes | 1.7 (1.2–2.5) |
0.005 | NS | NS | 2.2 (1.4–3.5) |
0.001 | ||
| VPC count (quartiles) 1st–3rd quartiles (0–152) |
NS | NS | NS | NS | ||||
| 4th quartile (>153) | 1.7 (1.2–2.3) |
0.001 | NS | NS | 2.2 (1.4–3.6) |
0.001 | ||
| HRT and DFA combined | ||||||||
| Normal HRT and Normal DFA1 | 1.0 | – | 1.0 | – | 1.0 | – | 1.0 | – |
| Normal HRT and Abnormal DFA1 | NS | NS | NS | 2.0 (1.1–3.8) |
0.034 | |||
| Abnormal HRT and Normal DFA1 | NS | NS | NS | NS | ||||
| Abnormal HRT and Abnormal DFA1 | 3.6 (2.4–5.3) |
<0.001 | 7.7 (3.7–16.0) |
<0.001 | 3.6 (1.8–7.4) |
<0.001 | 2.8 (1.5–5.1) |
0.001 |
*
N for multivariate model = 1,178 because HRT could not be categorized in 20 participants.
CVD = cardiovascular disease; DFA1 = short-term fractal scaling exponent; TO = heart rate turbulence onset; TS = heart rate turbulence slope; VPC = ventricular premature contractions.