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. Author manuscript; available in PMC: 2013 Apr 29.
Published in final edited form as: J Steroid Biochem Mol Biol. 2007 Sep 7;108(0):23–31. doi: 10.1016/j.jsbmb.2007.07.001

Figure 3. Effect of synthetic isoflavones on cell proliferation in the presence and absence of estradiol.

Figure 3

MCF-7 cells were treated with 5 μM of each of the agents alone and/or in the presence of 10 nM estradiol, and cell viability was measured as described in the experimental section. Estradiol (E2), 4-hydroxytamoxifen (4OHT), and genistein (Gen) were used as controls. The results were normalized against a control treatment with vehicle (DMSO). *, P < 0.0001 vs. control by unpaired t test, n = 6.